Cartridge Filling Services

Our Aston filling line delivers highly accurate cartridge filling with 100% non-destructive weight checks, rescue dosing, and minimal product loss.

See our comprehensive cartridge filling capabilities

Our Aston line is designed to scale with you

Our filling lines are isolator-based, fully automated, and designed to minimize product loss while meeting the highest regulatory standards. Below is a detailed breakdown of our Aston line’s cartridge filling capabilities.

Aston

Cartridge Size

3mL

Fill Speed

Up to ~9,000 vials/hr

Fill Volume

≥ 100μL

Regulatory Phase

Clinical and Commercial

Formulation Volume

Up to 800 L

Containment

Isolator-based

Pump

Peristaltic

Components Used

Ready-to-use (RTU)

Gas Overlay

Nitrogen

Weight Checks

100% in-process non-destructive

Every cartridge lot is manufactured to the highest global standards.

Every cartridge fill is executed under our fully validated quality system. Our lines are compliant with FDA (21 CFR 210, 211, 820), Annex 1, USP, EP, and JP. PUPSIT is available.

Visual inspection process

PUPSIT

Isolators

We support every phase of your fill-finish program.

From your first clinical batch to full-scale commercial production, our cartridge filling line is designed to support every phase of your program.

From fill-finish to final device, we manage it all

If your product requires an autoinjector or other delivery device, we connect you with the right downstream partner. We provide a unified quote covering fill-finish, device design, and assembly to give you full visibility into cost and timelines. We can also manage your fill-finish and device assembly project to offer a single point of contact through Argonaut.

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Let's discuss your cartridge fill requirements

Argonaut Non-Aseptic Fill Finish FAQs

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How do LyoDots work?

The proprietary adherent surface on a LyoDots ensures the lyophilized reagents maintain positional correctness and physical stability while allowing the production of formulated reagents to <2ul.

What shapes and morphology are LyoDots available in?

Various shapes are available including circular, rectangular, and semi-spherical.

How are LyoDots packaged?

LyoDots are delivered in sheets or reel-to-reel. Must be handled in a low humidity environment.

What size and volume are LyoDots delivered?

LyoDots thickness 0.15 to 1.00 mm. Volume: 0.1 uL – 50 uL.

Can I use LyoDots with robotic handling?

Yes. Use multi-axis robots/pick-place equipment with vacuum and effectors.

What is the shelf-life?

Dependent on components, usually 2 years.

What is the delivery capacity?

500,000 per week.

How many reactions are LyoDots designed for?

LyoDots are designed for cartridges or automation with 1 to 16 reactions. LyoDots reconstitute immediately without exhibiting out-gassing that can complicate microfluidics